18 results
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
relative with PBC ... Coordinated T & B cell ... cascade with T-cell ... Cholestasis #PBC ... #hepatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... - infiltrates (anemia ... Phosphorus CLL ... transformation of the CLL ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... • Neutropenia, anemia ... aplasia • ITP ... diagnosis #workup #oncology ... #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... PLT • Reticulocyte ... #Anemia #oncology ... #hematology #diagnosis
Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

 • Plasmacytoid Dendritic Cells (pDC) Neoplasms
 • BPDCN
 • BPDCN
Blastic Plasmacytoid ... Dendritic Cell ... (pDC) Neoplasms ... Plasmacytoid #Dendritic #Cell ... Neoplasm #diagnosis #oncology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... breast CA, small cell ... stone, Malignancy, PBC ... , Sickle cell, GVHD
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
hepatitis, Acute biliary ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... Disease, Sickle Cell ... Acute #algorithm #hepatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... = funny-shaped cells ... cytopenias (usually anemia ... Allogeneic stem cell ... #oncology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
transform into a RBC ... marrow failure: Aplastic ... , Intrinsic RBC ... defects (e.g. sickle cell ... Production #Index #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Lymphocytic Leukemia (CLL ... 5) Symptoms of anemia ... Transformation to large cell ... uw_IMresidency #CLL ... Lymphocytic #Leukemia #oncology