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diagnosis hematology algorithm causes workup injury management abnormal alkaline alp apml cell cholangitis cirrhosis coagulation comparison dic differentiation disorders disseminated
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis #pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Disease: Primary ... Biliary Cirrhosis ... Cholangitis #pathophysiology ... #pbc #psc #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Ducts - PBC ... , PSC, Alcoholic ... stricture, PSC,
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Liver Injury - Differential ... biliary obstruction ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... #algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... Cirrhosis (PBC) ... Pathophysiology ... bile ducts Differential ... diagnosis #workup #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... - Drugs - Primary ... (PBC) - Other ... Infiltrative diseases - PSC ... Diagnosis #Algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Bile Ducts • PSC ... Duct Stone • Biliary ... • Others #LFTs ... #Hepatology #LiverEnzymes
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
: INR/PT, aPTT(liver ... changes), high MCV anemia ... gastric bypass), LFT ... (liver disease) ... unclear, or if a primary
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... initiation • Differential ... fluid overload, PCC ... diagnosis #management #hematology ... #oncology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
malignancy (Especially acute ... protein C and S Pathophysiology ... DIC • Severe Liver ... Treatment: • Treat primary ... treatment #management #hematology
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