9 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase ... disturbance (obstructed liver ... Highest • Bone • Liver ... Intestine - Other causes ... Diagnosis #Algorithm #hepatology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Renal Disease, Liver ... Reticulocytosis • Liver ... #MCV #Classification ... #Hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
for Hemolytic Anemia ... : • Liver disease ... #Hemolytic #Anemia ... #classification ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
for decreased PLT ... : INR/PT, aPTT(liver ... changes), high MCV anemia ... bypass), LFT (liver ... #Workup #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
intralobular bile ducts causes ... cholestasis → Cirrhosis/Liver ... Labs: • Alkaline ... or higher • Liver ... diagnosis #workup #hepatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... Most cases diagnosed ... • Pernicious anemia ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
glucose by the liver ... www.ncbi.nlm.nih.gov/pmc ... contribution of liver ... 30mmHg) - Severe anemia ... #typea #typeb #classification
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
syndrome (PRIS) - acidosis ... bradycardia. renal/liver ... it should not cause ... result in lactic acidosis ... No pharmacologic
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Causes of Monoclonal ... Sarcoidosis) • Liver ... gastric tumors • Hematology ... Thalassemia, Sickle cell anemia ... • Other causes