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diagnosis differential hematology management coagulation disseminated elevation hemolytic intravascular lactate lactic rheumatology sjogrens syndrome typea typeb
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
for Hemolytic Anemia ... : • Liver disease ... MAHA: TTP, HUS, DIC ... #classification ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Severe Liver ... + Bleeding Treatment ... Treat primary cause ... #treatment #management ... #hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
www.ncbi.nlm.nih.gov/pmc ... perfusion - shock->treatments ... before beginning treatment ... 30mmHg) - Severe anemia ... #typea #typeb #classification
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... vasculitis: 10%-16% Liver ... renal tubular acidosis ... Adenocarcinoma Treatment ... lubricants • Pharmacologic
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