15 results
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 • Rivaroxaban
 • Apixaban
NOAC / DOAC Pharmacology ... • Apixaban • Dabigatran ... #NOAC #DOAC #Pharmacology ... #Prescribing #hematology ... #management #Direct
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Protamine sulfate - Dabigatran ... Andexxa), 4-factor PCC ... anticoagulation #doac ... #noac #pharmacology ... #hematology #reversal
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
Anticoagulants and DOACs ... VKA, Dabigatran ... Anticoagulants #DOACs ... anticoagulation #Switching #hematology ... #pharmacology
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Clotmaster #VTE #DOAC ... Anticoagulation #Dabigatran ... #Loading #DVT #Pharmacology ... #Hematology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
patients 5mg bid Dabigatran ... @Bloodman #DOAC ... Anticoagulation #Hematology ... #Pharmacology # ... #Rivaroxaban #Dabigatran
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Anticoagulation Management ... Warfarin, Apixaban, Dabigatran ... Anticoagulant #DOAC ... #Management #Table ... #Pharmacology #
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
heparin #LMWH #NOAC ... apixaban #Eliquis #dabigatran ... #Pradaxa #management ... #pharmacology #
REBEL Review 90: Weight Based 4 Factor PCC Dosing 

#Hematology #Management #Table #4FactorPCC #REBELReview #Pharmacology #Dosing
Based 4 Factor PCC ... Dosing #Hematology ... #Management #Table ... #4FactorPCC #REBELReview ... #Pharmacology #
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... modified factor Xa • Dabigatran ... not available #DOAC ... anticoagulant #hematology ... #management #pharmacology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
(DOAC interactions ... DOACs are substrates ... Dabigatran has moderate ... Chemotherapy #Oncology #Hematology ... Interactions #Table #Pharmacology