27 results
Aplastic Anemia Summary

 • Definition
 • Pathophysiology
 • DDx: AA vs Hypocellular MDS
 • Expectation
 •
Aplastic Anemia ... Definition • Pathophysiology ... #Aplastic #Anemia ... #diagnosis #oncology ... #hematololgy
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Significant ↓ PLT ... - infiltrates (anemia ... count • ↓Hg & PLT ... #Leukemia #Hematology ... #Oncology #Diagnosis
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Increased red cell ... Increased red cell ... Hemolysis #Hemolytic #Anemia ... Differential #Causes #Workup ... #Hematology #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
incompetent • CLL ... CLL Epidemiology ... • Neutropenia, anemia ... Leukemia #diagnosis #workup ... #oncology #hematology
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
hypercalcemia) • Anemia ... plus one of: • Anemia ... plasma clonal cell ... ratio >100 if FLC ... Diagnosis #Management #oncology
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
relative with PBC ... Pathophysiology ... cascade with T-cell ... Cholestasis #PBC ... #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... changes), high MCV anemia ... not required in all ... Diagnosis #Causes #Workup ... #hematology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
40 ml/min A - Anemia ... marrow plasma cell ... diseases, CML, ... MGUS #diagnosis #hematology ... #oncology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Mean corpuscular (cell ... Red cell distribution ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... Allogeneic stem cell ... Management #treatment #hematology ... #oncology