13 results
Cures for Sickle Cell disease 

#Sicklecell #sicklecelldisease #sicklecellanemia, #sicklecells #sickle #hematology #anemia #clinical #pediatrics #FOAM #FOAMed
Cures for Sickle ... sicklecelldisease #sicklecellanemia ... #sicklecells #sickle ... #hematology #anemia ... #clinical #pediatrics
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... , 1° PSC, Cystic ... Infiltrative Disease, Sickle ... Differential #Diagnosis #Causes ... #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... = nonspecific (nausea ... headache, malaise) → Acute ... Cr, ↓Glucose, ↓PLT ... #hepatology #obstetrics
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
HELLP Syndrome and Acute ... Fatty Liver of ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Algorithm Vascular Causes ... of Acute Liver ... , Sickle cell, GVHD ... diagnosis #algorithm #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... • Cirrhosis/acute ... metastasis • Fatty ... liver of pregnancy ... #hepatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... and petechiae Causes ... • ↓ WBC • ↓ PLT ... Marrow hypoplasia/fatty ... #oncology #hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
of lactate as a clinical ... www.ncbi.nlm.nih.gov/pmc ... cardiac output - Acute ... peritonitis - Acute ... 30mmHg) - Severe anemia
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
malignancy (Especially acute ... organ damage Clinical ... DIC • Severe Liver ... Treat primary cause ... Coagulation #diagnosis #causes
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Viral infections (acute ... Sarcoidosis) • Liver ... , Thalassemia, Sickle ... cell anemia • ... inflammation (acute