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Treatments for Sickle Cell disease

#Sicklecell #sicklecelldisease #sicklecellanemia, #sicklecells #sickle #hematology #anemia #clinical #pediatrics #FOAM #FOAMed
sicklecelldisease #sicklecellanemia ... sicklecells #sickle #hematology ... #anemia #clinical
Cures for Sickle Cell disease 

#Sicklecell #sicklecelldisease #sicklecellanemia, #sicklecells #sickle #hematology #anemia #clinical #pediatrics #FOAM #FOAMed
sicklecelldisease #sicklecellanemia ... sicklecells #sickle #hematology ... #anemia #clinical
Complications of sickle cell disease slide 2/3 

#Sicklecell #sicklecelldisease #sicklecellanemia, #sicklecells #sickle #hematology #anemia #clinical #pediatrics
sicklecelldisease #sicklecellanemia ... sicklecells #sickle #hematology ... #anemia #clinical
Complications of Sickle Cell Disease slide 1/3

#Sicklecell #sicklecelldisease #sicklecellanemia, #sicklecells #sickle #hematology #anemia #clinical #pediatrics #FOAM
sicklecelldisease #sicklecellanemia ... sicklecells #sickle #hematology ... #anemia #clinical
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... - Differential Diagnosis ... Abnormal peripheral smear ... #Differential #Diagnosis ... #Algorithm #hematology
complications of sickle cell disease slide 3/3

#Sicklecell #sicklecelldisease #sicklecellanemia, #sicklecells #sickle #hematology #anemia #clinical #pediatrics #FOAM
sicklecelldisease #sicklecellanemia ... sicklecells #sickle #hematology ... #anemia #clinical
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood Smear ... Peripheral #Blood #Smear ... #Analysis #hematology ... interpretation #clinical ... #anemia
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
Testing in Hemolytic Anemia ... LDH Peripheral smear ... #Hemolytic #Anemia ... Testing #workup #diagnosis ... #hematology #hemolysis
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
Autoimmune Hemolytic Anemia ... or negative - Smear ... C3 positive - Smear ... Pathophysiology #diagnosis ... #hematology
Sickle cell anemia and Howell Jolly bodies (nuclear remnants).

 - Dr. Abubaker Elshaikh
@ElshaikhMD

#SickleCell #HowellJolly #Body #Bodies
Sickle cell anemia ... Bodies #Pathology #Hematology ... #Smear #Clinical