19 results
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Diagnosis: • ... • Neutropenia, anemia ... thrombocytopenia • AIHA ... #workup #oncology ... #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Algorithm Acute ... Involvement - B-cell ... CD10 - T-cell ... Pelger-Huet, Macrocytic anemia ... - B-cell
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
- infiltrates (anemia ... Phosphorus CLL ... /Cytopenias • AIHA ... transformation of the CLL ... #Oncology #Diagnosis
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic ... Increased red cell ... Increased red cell ... #Causes #Workup ... #Hematology #Diagnosis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoid malignancy (CLL ... malignancies - B-cell ... malignancies -> CLL ... significance (MGUS), CLL ... #hematology #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Lymphocytic Leukemia (CLL ... Transformation to large cell ... fludarabine) 3) Monoclonal ... uw_IMresidency #CLL ... Lymphocytic #Leukemia #oncology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
- Differential Diagnosis ... Algorithm Extravascular ... • Sickle cell ... immune-complex hemolytic anemia ... #Hematology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
40 ml/min A - Anemia ... marrow plasma cell ... , B and T cell lymphoproliferative ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Lymphoma (HCV) • CLL ... Organomegaly+↑RBC/plt ... Coagulopathy) SMZL: • AIHA ... (-) hemolytic anemia ... #Diagnosis #Oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
No evidence of anemia ... insufficiency, Anemia ... to the plasma cell ... #Significance #hematology ... #diagnosis #oncology