6 results
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Monoclonal Gammopathy ... Significance (MGUS) - Differential ... Ig deposition disease ... #Diagnosis #hematology ... #oncology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
- Idiopathic monoclonal ... younger pts) Differential ... Diagnosis Monoclonal ... gammopathy of undetermined ... #anemia #hematology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
deposition disease ... tubulopathy • Monoclonal ... gammopathy of renal ... #AKI #Cancer #Oncology ... #Differential #
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Monoclonal Gammopathy ... hyperviscosity, lymphadenopathy ... #Gammopathy #Undetermined ... #Significance #hematology ... #diagnosis #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
it represents a monoclonal ... Causes of Monoclonal ... • Heavy chain disease ... endocrinopathy, monoclonal ... Gap #ProteinGap #differential
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... Organomegaly+↑RBC/plt ... Sneddon-Wilkinson disease ... #Monoclonal #Differential ... #Diagnosis #Oncology