25 results
Diffuse large B cell lymphoma (DLBCL) - Management and Treatment Algorithm

By Matthew Ho, MD PhD @MatthewHoMD

#Diffuse
Diffuse large B cell ... Management and Treatment ... DLBCL #Management #Treatment ... #Algorithm #oncology ... #hematology
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Primary Biliary Cirrhosis ... Coordinated T & B cell ... cascade with T-cell ... Primary #Biliary #Cirrhosis ... Pathophysiology #hepatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
lymphocytes/Mature B cell ... or basket cells ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... Allogeneic stem cell ... only curative treatment ... Diagnosis #Management #treatment ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Leukocyte count ↑ PLT ... Significant ↓ PLT ... count • ↓Hg & PLT ... #Leukemia #Hematology ... #Oncology #Diagnosis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
those with CLD (± cirrhosis ... months without treatment ... Liver #Failure #Cirrhosis ... #Hepatology #gastroenterology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Presence of CP or PC ... Family history of cirrhosis ... or fibrosis • Cirrhosis ... ) • Use of B-cell ... Indications #management #hepatology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
lymphocytes, smudge cells ... Transformation to large cell ... transformation) Treatment ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
The Liver Consult Primer - Guide to calling a consult
HPI:
 - Start with reason for consult
Gl History - Cirrhosis ... Vitals - LFTs, plt ... Calling #Referral #Hepatology ... #Gastroenterology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Release from blast cells ... • Induce blast cell ... fluid overload, PCC ... #oncology