10 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
AST > ALP): • Severe ... Ducts - PBC ... , PSC, Alcoholic ... Biliary stricture, PSC ... Algorithm #diagnosis #hepatology
Assessment and Treatment of Severe Asthma, According to Inflammatory Phenotypes, in Patients without a Response to
and Treatment of Severe ... Multidisciplinary Management ... #Management #PCC ... #Asthma #Severe ... Algorithm #Phenotypes #NEJM
An Integrated Multidisciplinary Approach to Assessment and Initial Management of Difficult-to-Treat and Severe Asthma in Adults.
Assessment and Initial Management ... Difficult-to-Treat and Severe ... glucocorticoids #Management ... #PCC #Asthma #Severe ... DifficultToTreat #Assessment #NEJM
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Diagnosis Algorithm Severe ... • Drugs • AIH ... Bile Ducts • PSC ... Others #LFTs #Hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
been reported (eg AIH-PBC ... If suspected, AIH ... Hepatitis (eg Viral) Management ... #Diagnosis #Management ... #Hepatology
Trick of the Trade: Naloxone Dilution for IV Use - Given that many ED overdose patients
doses that will reverse ... the chances of severe ... Administer 1-2 mL IV every ... #Management #EM ... #IM #PCC #Naloxone
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
More common in severe ... Moderate > 2/3 and severe ... fluid overload, PCC ... APML #diagnosis #management ... #hematology #oncology
Chest radiography showed perihilar opacities in both lungs with free air in the mediastinum (Panel A,
lungs with free air ... #Clinical #PCC # ... IM #EM #Pneumomediastinum ... #Influenza #NEJM
Proposed Schema for the Management of Pruritus in Primary Biliary Cholangitis (PBC). 

Cholestyramine up to 4g
Schema for the Management ... Biliary Cholangitis (PBC ... up to 60 mg/day every ... #Cholangitis #PBC ... #Management #Hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Presence of CP or PC ... family history of HCC ... infection with severe ... #Indications #management ... #hepatology