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rheumatology testing ana antibody antinuclear patterns systemic erythematosus lupus myopathy nuclear scleroderma sclerosis signs sle ssc symptoms workup
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
pattern: - PBC ... : - PBC, SSc ... , PBC/SSc OS, PBC ... #Patterns #differential ... #diagnosis #rheumatology
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
: • PBC, SSc, ... PBC/SSc OS, PBC/ ... SjS, SLE, RA, PBC ... #Patterns #differential ... #diagnosis #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune ... proximally to arms ... pericarditis • Hepatic: PBC ... acro-osteolysis, myositis ... #diagnosis #signs
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... disease • Non-autoimmune ... Malignancy (e.g. hematologic ... deficiencies • Autoimmune ... Antiribosomal P, APLA, PAC
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... - Differential ... % IBM • Anti-cytoplasmic ... Other Diseases: • PBC ... differential #diagnosis
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