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diagnosis erythematosus hematology hemophagocytic hlh lupus lymphohistiocytosis sle tuberculosis behcet calcium cppd deposition differential hemeonc inflammatory iris pseudogout pyrophosphate reconstitution
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Active TB: • ... Active TB: • ... : Active TB: • ... #Diagnosis #Management ... #Treatment #ActiveTB
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Active TB: • ... Active TB: • ... : Active TB: • ... #Diagnosis #Management ... #Treatment #ActiveTB
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
activity Anti-Ro ... block • Sjogren syndrome ... Treatment: • ... Summary #diagnosis #rheumatology ... #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... context of primary immune ... Antiribosomal P, APLA, PAC ... Erythematosus #Diagnosis #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... : Arterial (MCC-small ... Arthritis, AS Treatment ... #diagnosis #management ... signs #symptoms #rheumatology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Inflammatory Syndrome ... system may react ... worsening of that disease ... • Persistently active ... Differential #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... underlying genetic immune ... age, however the disease ... absent NK cell activity ... #treatment #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Central nervous system ... Adenocarcinoma Treatment ... muscarinic agonists • Active ... #Rheumatology # ... Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... system ... ▪ Autoimmune diseases ... absent NK-cell activity ... #Hematology #HemeOnc
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
deposit and can activate ... Acute Pseudogout: Treatment ... Crowned Dens Syndrome ... #Rheumatology # ... diagnosis #management
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