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syndrome syndromes workup acidosis amiodarone apml cardiology cardiomyopathy causes classification differentiation dysphagia elevation encephalopathy hematology immune induced inflammatory iris lactate
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
Pulmonary Renal ... Diagnosis Framework ... Diffuse alveolar ... aureus infection, ARDS ... #Diagnosis
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
elbows/wrists and knees ... • Diffuse systemic ... proximally to arms ... : scleroderma renal ... #rheumatology #diagnosis
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... hemorrhage (DAH) • Diffuse ... #differential # ... diagnosis #management ... #treatment
Leptospirosis Pathogen: Leptospira (interrogans, kirschneri, noguchii) Risk Factors: • Occupational exposure - Farmers, ranchers, trappers, veterinarians • Recreational
Disease: Jaundice + renal ... failure • Severe pulmonary ... disease ARDS Diagnosis ... #microbiology #diagnosis ... #treatment #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... initiation • Differential ... Anaphylaxis, Acute Renal ... #management #hematology
Dysphagia - Differential Diagnosis Framework Symptom | Diagnosis • Solid-food dysphagia present for months to years | Mechanical
Dysphagia - Differential ... Intermittent: Diffuse ... disorder → EGD Treatment ... #Diagnosis #Management ... #gastroenterology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... Diagnosis The ... www.ncbi.nlm.nih.gov/pmc ... before beginning treatment ... output - Acute pulmonary
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
starting amiodarone treatment ... organizing pneumonia, ARDS ... • Patchy or diffuse ... macrophages Treatment ... #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Immunosuppressive agents, Renal ... Reversible course Differential ... epilepticus Treatment ... underlying cause • Treatment ... #management #neurology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Lymphadenitis, pulmonary ... lymphadenitis, pulmonary ... Leishmaniasis Differential ... Inflammatory #Syndrome #Differential ... #Diagnosis #Management
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