7 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
elbows/wrists and knees ... • Diffuse systemic ... sclerosis (DcSSc; diffuse ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Pancreatic cystic lesions (PCLs)
 - classified into simple retention cysts, pseudocysts and cystic neoplasms 
 -
histological and clinical ... modalities for PCL ... lesions #PCLs #gastroenterology ... #diagnosis #management ... #differential
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... fraction < 20% Differential ... hepatitis • Pulmonary ... #management #treatment ... #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Imaging: CXR- pulmonary ... initiation • Differential ... Diagnosis: Infection ... fluid overload, PCC ... #management #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... pneumonitis • Diffuse ... enteropathy, and diffuse ... #Rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... • Nucleolar: Diffuse ... , Interstitial Pulmonary ... ANA #patterns #rheumatology ... #diagnosis #differential
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
abdominal pain, Diffuse ... filling +++ (risk of pulmonary ... leak #syndrome #diagnosis ... #management #timeline ... #treatment #rheumatology