9 results
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
injury, though ... been reported (eg AIH-PBC ... , AIH diagnosis ... #AIH #Diagnosis ... #Management #Hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... - Differential Diagnosis ... Algorithm for Transaminitis ... Burak @kwburak #LFTs ... #diagnosis #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... Diagnosis Hepatocellular ... #Diagnosis #Causes ... #Acute #algorithm ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... Algorithm Vascular ... #injury #hepatitis ... #algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Drugs • AIH ... • Alcoholic hepatitis ... • Others #LFTs ... #Hepatology #LiverEnzymes
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
: Liver Injury ... Infections: Hepatitis ... #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... Check Acute viral hepatitis ... #chemistry #diagnosis ... #differential #Hepatology ... transaminitis #LFTs
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
(AAH) Drug-Induced ... Liver Injury (DILI ... ) Viral Hepatitis ... Failure #Cirrhosis #Hepatology ... #diagnosis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... #differential #Diagnosis ... #algorithm #gastroenterology ... #hepatology