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treatment hematology adultonset causes coagulation disease disseminated hemeonc hemophagocytic hit hlh induced intravascular lymphohistiocytosis sjogrens stills summary syndrome thrombocytopenia
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
Factors: • SICU ... > MICU, ♀, ↑Age ... : • Clinical Suspicion ... A/C if clinical ... #Hematology #HemeOnc
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... 100mg/dL) - Heparin ... #Coagulation #diagnosis ... causes #treatment #management ... #hematology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Fever, Arthralgia/arthritis ... MAS, Visceral, DIC ... splenomegaly • Hepatic ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Cytopenia +++ (Plt ... , Hb), Hepatic dysfunction ... of emergency, ICU ... #management #treatment ... #summary #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
salivary ducts Clinical ... phenomenon (16%) MSK ... Arthralgia and Arthritis ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
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