10 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Ducts - PBC ... , PSC, Alcoholic ... Biliary stricture, PSC
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Pathophysiology ... cholestasis → Cirrhosis/Liver ... or higher • Liver ... bile ducts Differential ... #workup #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis ... #hepatology
Posterior Cruciate Ligament (PCL) Injury: Pathogenesis and Clinical Findings
Classification of PCL Iniuries
 • Partial: Translation <
Posterior Cruciate ... Ligament (PCL) ... #Injury #MSK #Sports ... #pathophysiology ... classification #diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... initiation • Differential ... fluid overload, PCC ... Differentiation #Syndrome #APML ... #hematology #oncology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH ... Defects, Drugs, Liver ... Defects: Sickle cell anemia ... Laboratory Tests ... #Diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... : INR/PT, aPTT(liver ... K), H. pylori test ... changes), high MCV anemia ... #Workup #hematology
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
www.ncbi.nlm.nih.gov/pmc ... www.ncbi.nlm.nih.gov/pmc ... www.ncbi.nlm.nih.gov/pmc ... deficiencies • Renal, liver ... #differential #
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Sarcoidosis) • Liver ... autoimmune hepatitis, PBC ... , PSC, Viral hepatitis ... Gap #ProteinGap #differential ... #diagnosis #hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... Diagnosis The ... www.ncbi.nlm.nih.gov/pmc ... tests before beginning ... 30mmHg) - Severe anemia