11 results
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
(PBC) - Summary ... PBC Epidemiology ... 30-65 years PBC ... intralobular bile ducts causes ... #hepatology
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
asymptomatic at diagnosis ... liver disease management ... #Cholangitis #diagnosis ... #management #summary ... #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
- Differential Diagnosis ... Bile Ducts • PSC ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology ... #Algorithm #Causes
Management of Jehovah's Witness patient in ICU 

Clarify which products may be used 
 - Discuss
Management of Jehovah's ... Witness patient in ICU ... pts will accept PCC ... twitter.com/PulmCrit #Checklist ... #CriticalCare #
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Presence of CP or PC ... Family history of cirrhosis ... or fibrosis • Cirrhosis ... #Indications #management ... #hepatology
ICU Pre-Rounding Bundle Checklist
VITALS: trends!
 • Important to know if the pt is getting better or
Bundle Checklist ... plateau) • AC/PC ... (PC/PEEP/RR/FiO2 ... #CriticalCare # ... Management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
opacities • Diagnosis ... • Differential Diagnosis ... organ dysfuxtion, ICU ... fluid overload, PCC ... #management #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Liver disease: Cirrhosis ... autoimmune hepatitis, PBC ... , PSC, Viral hepatitis ... #differential #diagnosis ... #hematology
Acute Altered Mental Status - Rapid Response Management

1) Ask while en route: vitals, hyper/hypoactive, POC glucose,
Rapid Response Management ... hyper/hypoactive, POC ... the underlying cause ... mental #status #Management ... #criticalcare #