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treatment differential hematology algorithm cholangitis activetb gastroenterology latenttb liver oncology psc sclerosing screening summary tb tuberculosis abscess acute aflp alkaline
Primary sclerosing cholangitis (PSC) - Malignancy Screening and Surveillance Recommendations Cholangiocarcinoma - Annual US or
Primary sclerosing ... cholangitis (PSC ... #cholangitis #PSC ... #Malignancy #Cancer ... Gastroenterology #Management
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
The 6 C’s of Primary ... asymptomatic at diagnosis ... • CANCER - PSC ... #Primary #Sclerosing ... #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... Pancreatic Pseudocyst, Cancer ... #algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Cirrhosis (PBC) ... - Summary PBC ... 30-65 years PBC ... intralobular bile ducts causes ... #workup #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Intestine - Other causes ... - Drugs - Primary ... biliary Cholangitis (PBC ... Infiltrative diseases - PSC ... #Algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
- Differential Diagnosis ... Bile Ducts • PSC ... • Pancreatic cancer ... Others #LFTs #Hepatology ... #Algorithm #Causes
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... Cr, ↓Glucose, ↓PLT ... ) Differential Diagnosis ... liver transplant center ... Liver #Pregnancy #hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Imaging: CXR- pulmonary ... opacities • Diagnosis ... • Differential Diagnosis ... fluid overload, PCC ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Cytopenia +++ (Plt ... assessment+++ Primary ... B-LNH), solid cancers ... Drugs, Unknown cause ... #management #treatment
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Treatment: • Treat primary ... cause • Correct ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
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