9 results
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Anti-Synthetase Syndrome ... : Jo-1, PL7, PL12 ... MSAs #clinical #diagnosis ... #rheumatology # ... table
Original and Simplified PESI PulmonaryEmbolism #Diagnosis #EM #IM #PCC #PESI #sPESI #risk #score #PE #Table
PulmonaryEmbolism #Diagnosis ... #EM #IM #PCC #PESI ... #sPESI #risk #score ... #PE #Table
Pulmonary Embolism Severeity Index - estimates 30d mortality #Diagnosis #Management #EM #IM #PCC #PESI #sPESI #risk
30d mortality #Diagnosis ... #Management #EM ... #IM #PCC #PESI ... #sPESI #risk #score
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
biliary cirrhosis (PBC ... La) - Sjogren's syndrome ... Associations #diseases #diagnosis ... #table #rheumatology ... #antibodies
Borrelia recurrentis on Peripheral Blood Smear
23M Somali refugee recently arrived w/severe abd pain, confusion and fever
12.5, WBC 14, Plt ... Syndrome: 3d of ... The table below ... and convalescent antibodies ... or PenG 800K U IM
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... Antiribosomal P, APLA, PAC ... Erythematosus #Diagnosis ... #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... Hypocomplementemia • Can cause ... neuropathy, transverse myelitis ... #Rheumatology # ... Diagnosis #Management
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential Diagnosis ... RP-ILD), dermato-rheumatologic ... statins - probably caused ... Other Diseases: • PBC ... #Myopathy #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... caused by uncontrolled ... : HScore a. ... inhibitors, anti-IFN-γ antibodies ... #Management #Hematology