17 results
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Warm Antibody Autoimmune ... • Blood smear: Differential ... 2) LOOK FOR a cause ... #diagnosis #management ... #treatment #rheumatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis ... reported (eg AIH-PBC ... regarding need for treatment ... BryanCUlrich #Autoimmune ... AIH #Diagnosis #Management
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Myasthenia Gravis is an autoimmune ... Hodgkin lymphoma - Autoimmune ... Clinical Picture ... life-threatening Differential ... Gravis #diagnosis #management
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... Lung Abscess - Clinical ... Leukocytosis, anemia ... of PCN allergy ... #causes #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... and petechiae Causes ... • ↓ WBC • ↓ PLT ... Treatment: ... hematology #diagnosis #management
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
the Journal of Clinical ... www.ncbi.nlm.nih.gov/pmc ... www.ncbi.nlm.nih.gov/pmc ... www.ncbi.nlm.nih.gov/pmc ... pathophysiology #differential
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... www.ncbi.nlm.nih.gov/pmc ... / hypoxemia -> focus ... before beginning treatment ... 30mmHg) - Severe anemia
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Cytopenia +++ (Plt ... solid cancers • Autoimmune ... Treatment: • ... Lymphohistiocytosis #diagnosis #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Cirrhosis, ETOH, autoimmune ... hepatitis, PBC, ... PSC, Viral hepatitis ... Thalassemia, Sickle cell anemia ... Gap #ProteinGap #differential
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... Summary Causes ... Hyperthyroidism - Autoimmune ... Dermatomyositis Clinical ... #causes #treatment