17 results
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... and petechiae Causes ... • ↓ WBC • ↓ PLT ... #oncology #hematology ... #diagnosis #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
autoimmune hepatitis, PBC ... , PSC, Viral hepatitis ... gastric tumors • Hematology ... Thalassemia, Sickle cell anemia ... differential #diagnosis #hematology
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Major Clinical Trials ... NEJM 1999 - ICU FOCUS ... - NEJM 2018 - Cardiac ... unnecessary and cause ... Transfusion #Thresholds #Hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
www.ncbi.nlm.nih.gov/pmc ... / hypoxemia -> focus ... perfusion - Cardiac ... failure - Low cardiac ... 30mmHg) - Severe anemia
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... Treat primary cause ... Coagulation #diagnosis #causes ... #treatment #management ... #hematology
Ventricular Fibrillation - Transesophageal echo
POC-TEE in cardiac arrest: Instant recognition of shockable rhythm during a pulse
Transesophageal echo POC-TEE ... in cardiac arrest ... Echocardiogram #POCUS ... #Cardiology #Clinical
Palpitations - Differential Diagnosis Framework

What?
• It is an unpleasant awareness or sensation that the heart is
muscle twitching CARDIAC ... Nonarrhythmic Cardiac ... Hyperthyroidism • Anemia ... palpitations: PVC ... #Palpitations #Cardiology
Tamponade Masked in Pulmonary Hypertension

Signs of Tamponade can be masked by pulmonary hypertension! 1.2L drained. Read
www.ncbi.nlm.nih.gov/pmc ... sided collapse) #Clinical ... #POCUS #Cardiology ... Echocardiogram #A4C #Cardiac
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Antiribosomal P, APLA, PAC ... 5% of patients Cardiac ... Cytopenias • Cardiac ... • Anemia of inflammation
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... autoimmune hemolytic anemia ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management