17 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody Testing ... : - PBC, SSc ... , PBC/SSc OS, PBC ... #differential #diagnosis ... #rheumatology
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
asymptomatic at diagnosis ... for efficacy is challenged ... #Cholangitis #diagnosis ... #management #summary ... #Hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
) - Summary PBC ... intralobular bile ducts causes ... Proximal limb muscle wasting ... patients • +ANA ... #workup #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
- Differential Diagnosis ... • Ischemia • Autoimmune ... Bile Ducts • PSC ... • Cirrhosis (any ... #Algorithm #Causes
Predicting an anatomically and/or physiologically challenging airway is not a straightforward task by any stretch of
elective surgery setting ... emergency airway management ... on anatomical challenges ... #Diagnosis #EM # ... PCC #Heaven #Criteria
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis ... reported (eg AIH-PBC ... Hepatitis (eg Viral) Management ... BryanCUlrich #Autoimmune ... #Management #Hepatology
Fluid Responsiveness and Fluid Tolerance Testing - OnePager Summary
Fluid resuscitation can be beneficial when required or
Fluid Tolerance Testing ... measurement of CO via a PAC ... cardiac output causes ... #diagnosis #criticalcare ... #management
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune ... pericarditis • Hepatic: PBC ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #symptoms #testing
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
opacities • Diagnosis ... • Differential Diagnosis ... fluid overload, PCC ... #management #hematology ... #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Cirrhosis, ETOH, autoimmune ... hepatitis, PBC, ... PSC, Viral hepatitis ... #differential #diagnosis ... #hematology