12 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... Testing - Nuclear ... : - PBC, SSc ... , PBC/SSc OS, PBC ... #Testing #Nuclear
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Testing - Nuclear ... pattern: • SSc, PBC ... : • PBC, DM, other ... ARUPConsult @ARUPLabs #ANA ... #Testing #Nuclear
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Workup History ... smear, HIV/HCV testing ... thrombocytopenia is unclear ... or if a primary hematologic ... #Workup #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
) - Summary PBC ... intralobular bile ducts causes ... patients • +ANA ... cholangitis #diagnosis #workup ... #hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis ... reported (eg AIH-PBC ... Autoantibodies: Auto-Nuclear ... ANA) & Anti-Smooth ... #Hepatology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune ... pericarditis • Hepatic: PBC ... Scleroderma #SSc #rheumatology ... signs #symptoms #testing ... #workup
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... Spot PC (protein ... antigen, hepatitis C antibody ... infections are common causes ... #workup #diagnosis
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... Spot PC (protein ... antigen, hepatitis C antibody ... infections are common causes ... glomerular #disease #workup
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... Cirrhosis, ETOH, autoimmune ... hepatitis, PBC, ... PSC, Viral hepatitis ... gastric tumors • Hematology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Management Summary ... Prevalence: 1-2 cases ... autoimmune response ... disorders • Testing ... antibody that works