19 results
diagnosis hepatology biliary pbc algorithm differential rheumatology cholangitis hemophagocytic hepatitis hlh lymphohistiocytosis summary syndrome aih anemia antibodies aplastic apml associations
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... Cirrhosis - Diagnosis ... pregnancy Diagnose PBC ... consistent with PBC ... #PBC #Primary
Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
Primary Biliary ... Cirrhosis - Pathophysiology ... relative with PBC ... Cholestasis #PBC ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Cirrhosis (PBC) ... - Summary PBC ... 30-65 years PBC ... intralobular bile ducts causes ... diagnosis #workup #hepatology
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
The 6 C’s of Primary ... liver disease management ... #Primary #Sclerosing ... Cholangitis #diagnosis #management ... #summary #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Ischemia • Autoimmune ... Bile Ducts • PSC ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
common in SLE, autoimmune ... microsomal) - Autoimmune ... , Anti-gp210 - Primary ... biliary cirrhosis ... (PBC) Anticentromere
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... , PBC, PSC, IgG4 ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis ... hepatitis: < 1 • Cirrhosis
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... reported (eg AIH-PBC ... regarding need for treatment ... AIH #Diagnosis #Management ... #Hepatology
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Presence of CP or PC ... Family history of cirrhosis ... or fibrosis • Cirrhosis ... #Indications #management ... #hepatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
assessment+++ Primary ... solid cancers • Autoimmune ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
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