17 results
diagnosis hepatology differential algorithm injury liver syndrome treatment acute aih anemia antibodies aplastic apml associations autoantibodies biliary cholangitis classification common
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Other: NAFLD, Autoimmune ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... Acute #algorithm #hepatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
common in SLE, autoimmune ... hepatitis Anti-CCP ... Primary biliary cirrhosis ... (PBC) Anticentromere ... diagnosis #table #rheumatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Ischemia • Autoimmune ... Bile Ducts • PSC ... • Alcoholic hepatitis ... Infiltrative • Cirrhosis ... Diagnosis #Algorithm #Causes
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
(PBC) - Summary ... PBC Epidemiology ... 30-65 years PBC ... intralobular bile ducts causes ... Diagnosis: • Viral hepatitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... : Autoimmune hepatitis ... , PBC, PSC, IgG4 ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... reported (eg AIH-PBC ... (eg Viral) Management ... #Diagnosis #Management ... #Hepatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
, ETOH, autoimmune ... hepatitis, PBC, ... PSC, Viral hepatitis ... gastric tumors • Hematology ... differential #diagnosis #hematology
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... Presence of CP or PC ... or fibrosis • Cirrhosis ... #Indications #management ... #hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
fluid overload, PCC ... APML #diagnosis #management ... #hematology #oncology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Liver diseases and hepatitis ... : Pneumonia • Autoimmune ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
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