26 results
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Cirrhosis - Diagnosis ... PBC if 2/3 criteria ... consistent with PBC ... #PBC #Primary ... #Biliary #Cirrhosis
Primary Biliary Cirrhosis (PBC) - Diagnosis Algorithm

#Primary #Biliary #Cirrhosis #PBC #Diagnosis #Algorithm #hepatology
Primary Biliary ... Cirrhosis (PBC) ... - Diagnosis Algorithm ... #Cirrhosis #PBC ... #hepatology
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Cirrhosis - Pathophysiology ... relative with PBC ... cell mediated autoimmune ... Cholestasis #PBC ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Cirrhosis (PBC) ... - Summary PBC ... 30-65 years PBC ... • Fatigue PBC ... #Cirrhosis #PBC
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Ducts - PBC ... , PSC, Alcoholic ... Congenital, Others, Cirrhosis ... - CBD stone, Biliary ... stricture, PSC,
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... - Differential Diagnosis ... Other: NAFLD, Autoimmune ... Malignancy, 1° PBC ... , 1° PSC, Cystic
Causes of Fat Malabsorption - Differential Diagnosis
Biliary Duct Obstruction
 • Autoimmune— PBC, PSC
 • Infection— liver
Causes of Fat Malabsorption ... - Differential Diagnosis ... Biliary Duct Obstruction ... PBC, PSC • Infection ... #Causes
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... , PBC, PSC, IgG4 ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis ... hepatitis: < 1 • Cirrhosis
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
) PSC is a chronic ... • COVERT - PSC ... patients with PSC ... pathogenesis of PSC ... • CANCER - PSC
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Intestine - Other causes ... Cholangitis (PBC ... Infiltrative diseases - PSC ... #Algorithm #hepatology