14 results
differential hepatology rheumatology treatment algorithm hepatitis injury liver systemic aih altered ams apml biliary chagas cholangitis cirrhosis classification coagulation criticalcare
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Other: NAFLD, Autoimmune ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... #Causes #Acute
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Cirrhosis (PBC) ... - Summary PBC ... 30-65 years PBC ... intralobular bile ducts causes ... #workup #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular Causes ... , PBC, PSC, IgG4 ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... subclinical disease to acute ... reported (eg AIH-PBC ... BryanCUlrich #Autoimmune ... #Management #Hepatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune ... pericarditis • Hepatic: PBC ... (primary biliary ... #diagnosis #signs ... symptoms #testing #workup
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
• Rare: DAH, acute ... , Anaphylaxis, Acute ... fluid overload, PCC ... #management #hematology ... #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Cirrhosis, ETOH, autoimmune ... hepatitis, PBC, ... PSC, Viral hepatitis ... #differential #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Cytopenia +++ (Plt ... assessment+++ Primary ... solid cancers • Autoimmune ... #management #treatment ... #summary #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
malignancy (Especially acute ... Treatment: • Treat primary ... cause • Correct ... #Coagulation #diagnosis ... #management #hematology
Acute Altered Mental Status - Rapid Response Management 1) Ask while en route: vitals, hyper/hypoactive, POC glucose,
Acute Altered Mental ... Rapid Response Management ... hyper/hypoactive, POC ... Workup 5) Treat ... the underlying cause
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