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hepatology algorithm differential rheumatology cholangitis pbc cirrhosis injury liver summary workup acute alp antibodies associations autoantibodies diseases elevation hemophagocytic hepatitis
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Intestine - Other causes ... - Drugs - Primary ... (PBC) - Other ... Infiltrative diseases - PSC
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... PBC if 2/3 criteria ... consistent with PBC ... #PBC #Primary ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... Cirrhosis (PBC) ... intralobular bile ducts causes ... Labs: • Alkaline ... #hepatology
Algorithm for the Diagnosis of Primary Biliary Cholangitis (PBC). US, ultrasound; MRCP, magnetic resonance cholangiopancreatography; ALP,
of Primary Biliary ... Cholangitis (PBC ... cholangiopancreatography; ALP, alkaline ... #PBC #Algorithm ... #Diagnosis #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... - Differential Diagnosis ... Other: NAFLD, Autoimmune ... Malignancy, 1° PBC ... , 1° PSC, Cystic
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
The 6 C’s of Primary ... to multi-focal biliary ... asymptomatic at diagnosis ... #Primary #Sclerosing ... #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
- Differential Diagnosis ... • Ischemia • Autoimmune ... Bile Ducts • PSC ... Duct Stone • Biliary ... #Algorithm #Causes
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular Causes ... , PBC, PSC, IgG4 ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
, Anti-gp210 - Primary ... biliary cirrhosis ... (PBC) Anticentromere ... Associations #diseases #diagnosis ... #table #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune ... pericarditis • Hepatic: PBC ... (primary biliary ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
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