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hematology algorithm liver anemia biliary encephalopathy injury neurology syndrome treatment abscess acute aflp alkaline alp altered ams aplastic apml ascites
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... #Diagnosis #Causes ... Acute #algorithm #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Diagnosis Algorithm ... Intestine - Other causes ... biliary Cholangitis (PBC ... Infiltrative diseases - PSC ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
) - Summary PBC ... Pathophysiology ... intralobular bile ducts causes ... bile ducts Differential ... #workup #hepatology
Causes of Biliary Dilatation - Differential Diagnosis • Physiological: ↑ Age, Cholecystectomy, Opioid dependence, Post-sphincterotomy •
Causes of Biliary ... Dilatation - Differential ... pancreatitis, PSC ... #differential # ... diagnosis #hepatology
Torsades de Pointes (TdP): Pathogenesis and Clinical Findings Polymorphic ventricular tachycardia initiated by PVC in the setting
tachycardia initiated by PVC ... dePointes #TdP #Diagnosis ... #pathophysiology ... #cardiology #causes ... #differential
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Liver Enzymes - Differential ... Diagnosis Algorithm ... Bile Ducts • PSC ... Others #LFTs #Hepatology ... #Causes
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Vascular Causes ... Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... initiation • Differential ... fluid overload, PCC ... #management #hematology ... #oncology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... Cr, ↓Glucose, ↓PLT ... infiltration) Differential ... Liver #Pregnancy #hepatology ... #management #pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
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