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diagnosis oncology biliary cirrhosis differentiation emergencies hemeonc hepatology management oncologic pbc primary rheumatology scleroderma sclerosis signs ssc symptoms syndrome systemic
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
) - Summary PBC ... Proximal limb muscle wasting ... bile ducts Differential ... fungal, viral infections ... #workup #hepatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
pericarditis • Hepatic: PBC ... primary biliary cholangitis ... calcinosis • Pulmonary ... signs #symptoms #testing ... #workup
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Imaging: CXR- pulmonary ... initiation • Differential ... Diagnosis: Infection ... fluid overload, PCC ... diagnosis #management #hematology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
if SSTI or port infection ... work-up - If febrile ... days → add fungal work-up ... syndrome): - Hematologic ... renal failure, pulmonary
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