52 results
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis

#pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Disease: Primary ... Biliary Cirrhosis ... Cholangitis #pathophysiology ... #pbc #psc #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Ducts - PBC ... , PSC, Alcoholic ... Biliary stricture, PSC ... Algorithm #diagnosis #hepatology
NAFLD / NASH Progression Timeline
Healthy Liver → NAFLD/NASH → 0.25-3.2%/year → Cirrhotic NASH → 0.3-2.6%/year →
Timeline Healthy Liver ... 0.3-2.6%/year → HCC ... Cirrhotic NASH ... NASH → HCC Risk ... Progression #Timeline #hepatology
Summary table of comparison of the difference between primary biliary cholangitis (PBC) and primary sclerosing cholangitis
difference between primary ... biliary cholangitis (PBC ... ) and primary sclerosing ... cholangitis (PSC ... #differential #hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
pregnancy Diagnose PBC ... Liver biopsy findings ... consistent with PBC ... #PBC #Primary ... Diagnosis #Algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Cirrhosis (PBC) ... Pathophysiology ... /Liver failure ... or higher • Liver ... diagnosis #workup #hepatology
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Cirrhosis - Pathophysiology ... relative with PBC ... Cholestasis #PBC ... #Cirrhosis #Pathophysiology ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... ALT < 5x ULN • NAFLD ... Bile Ducts • PSC ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology
Cirrhosis - Pathophysiology
 - Ascites Formation
 - Dilutional Hyponatremia
 - Hepatorenal Syndrome
 - Spontaneous Infections

#Cirrhosis #Pathophysiology
Cirrhosis - Pathophysiology ... Infections #Cirrhosis ... #Pathophysiology ... #hepatology #liver
Primary Biliary Cirrhosis (PBC) - Diagnosis Algorithm

#Primary #Biliary #Cirrhosis #PBC #Diagnosis #Algorithm #hepatology
Primary Biliary ... Cirrhosis (PBC) ... #Biliary #Cirrhosis ... #PBC #Diagnosis ... #Algorithm #hepatology