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diagnosis differential algorithm injury liver management oncology apml causes criteria dermatology dermatosis differentiation erythematosus febrile gap globulin hbv hepatitis hepatitisb
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... obstruction, HELLP Syndrome ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... #algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis ... diagnosis #algorithm #hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... • Rare: DAH, acute ... fluid overload, PCC ... Differentiation #Syndrome ... diagnosis #management #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
capillary leak syndrome ... Organomegaly+↑RBC/plt ... WAIHA • CAD • PCH ... Evans • ITP • Cl-NH ... Paraproteinemias #Hematology
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis) Major criteria 1. Abrupt onset of tender
Criteria for Sweet Syndrome ... (Acute Febrile ... count >10 x 10^3/pL ... #Acute #Febrile ... Criteria #Diagnosis #Hematology
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Presence of CP or PC ... family history of HCC ... immunosuppression • Acute ... > 3 mg/dL) or acute ... Indications #management #hepatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... autoimmune hepatitis, PBC ... , PSC, Viral hepatitis ... gastric tumors • Hematology ... differential #diagnosis #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... Malignancy (e.g. hematologic ... Pleural effusions • Acute ... Antiribosomal P, APLA, PAC ... La, anti-Jo-1, SCL
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