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management rheumatology treatment dermatology lupus druginduced neurology sle syndrome acromegaly alkaline alp anemia antinxp2 antinxp2dm cerebritis cns coagulation comparison dermatomyositis
Cutaneous Mucormycosis Eschar 30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
Diagnosis? ... immunosuppressed pts ... mucor cases may ... #dermatology #skin ... #clinical #photo
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... organ damage Clinical ... involvement (2%) Cutaneous ... #Coagulation #diagnosis ... #management #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... • Immunologic Workup ... Rare (SSA+ for cutaneous ... Discontinuation of causal ... #diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... permeability Diagnosis ... #neurology #rheumatology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
GrepMed Handbook Clinical ... malignancy) • Cutaneous ... malignancy Pathophysiology ... and Workup: • ... or refractory cases
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... Most cases diagnosed ... membrane into the CNS ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes
Rickettsialpox Eschar 40 homeless male from NY admitted with fever, chills, headache, myalgias. Diagnosis? Rickettsialpox R akari classic
Diagnosis? ... Pts can recover ... #rakari #clinical ... #photo #skinrash ... #dermatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome Diagnosis ... Hypocomplementemia • Can cause ... salivary ducts Clinical ... skin (xerosis) • Cutaneous ... Nephrogenic DI Hematologic
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Prevalence: 1-2 cases ... Person Syndrome Pathophysiology ... Clinical Manifestations ... positive in 2/3 of pts ... antibody that works
Anemia of Hospitalization - Pathophysiology Why does the Hgb/Hct drop in the first two days during hospitalization? Interestingly,
Hospitalization - Pathophysiology ... a drop in your pts ... the Journal of Clinical ... phlebotomy/ blood work ... #pathophysiology
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