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management dermatology differential oncology syndrome algorithm anemia antinxp2 antinxp2dm aplastic cardiology cerebritis cns coagulation dermatomyositis dic disorders disseminated eosinophil erythematosus
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... (common causes ... glucocorticoid treatment ... #Differential #diagnosis ... #hematology #eosinophilia
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
autoantibodies that will cause ... permeability Diagnosis ... #neurology #rheumatology ... #cerebritis #diagnosis ... #management #treatment
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
+ Bleeding Treatment ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... count ↑ PLT • ↑ PBS ... • (Peripheral eosinophilia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... - Hepatitis, eosinophilic ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... Rule out other causes ... and lower jaw Treatment ... SAPHO #Syndrome #Rheumatology ... #Dermatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... progressive) EGPA (Eosinophilic ... Polyangiitis): • Eosinophilia ... tract, and often causes ... #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome Diagnosis ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
Acute Recurrent Pericarditis = recurrence of Acute Pericarditis (AP) after free interval >4-6 weeks without symptoms, >1/4
symptoms, >1/4 of AP cases ... manifestations, eosinophilia ... #Pericarditis #diagnosis ... #management #treatment ... #rheumatology #
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
subcutaneous edema Pts ... Muscle atrophy may cause ... positive patients Treatment ... Dermatomyositis #diagnosis ... #management #rheumatology
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