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diagnosis differential eosinophilia clinical dermatology drugreaction skinrash anemia extravascular hemolysis hemolytic management agglutinin algorithm arterial cold disease embolism legs myopathy
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... hemoglobinuria (PNH ... #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Cold AIHA • Alloimmune ... • PCH • PNH ... Diagnosis #Algorithm #Causes ... #Hematology
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS represents
Syndrome): Formerly ... medication (in this case ... Images #Clinical #Dermatology ... Eosinophilia #Photo ... #UCSDH
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS represents
Syndrome): Formerly ... medication (in this case ... Images #Clinical #Dermatology ... Eosinophilia #Legs #Photo ... #UCSDH
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS represents
Syndrome): Formerly ... medication (in this case ... Images #Clinical #Dermatology ... Eosinophilia #Trunk #Photo ... #UCSDH
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... Parasites Drugs: - DRESS ... (vasculitis / autoimmune ... Hypereosinophilic Syndrome ... #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Nephrotic Syndrome ... - Disseminated intravascular ... coagulation and other causes ... - COVID-19 - PNH ... pathophysiology #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral infection, autoimmune ... CLL (older) • Autoimmune ... the RBCs causing intravascular ... hemolytic #anemia #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... be any age) Autoimmune ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... #Rheumatology #
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
TAFRO TAFRO syndrome ... mesothelioma, etc - Autoimmune ... cell lymphoma - Intravascular ... histopathologic changes in LNs ... diagnosis #management #rheumatology
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