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Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework

STRUCTURAL:
- PFO: paradoxical emboli
- Popliteal

Causes of Arterial ... artery aneurysm: Causes ... APLS:PLT ↓ HEMATOLOGIC ... neoplasms - PNH ... Diagnosis #clots #hematology

Childhood Immunization Schedule: Why we immunize
• Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened

replicates within CNS ... cause quadriplegia ... invade URT & via hematologic ... induces vascular & CNS ... CNS and hematologic

Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
• Myocardium:
- Heart failure
- CAD/ACS
- Valvulopathy
• Electrical:
-

Cardiovascular Causes ... Tamponade Pulmonary Causes ... - Water - Pus ... syndrome Other Causes ... Transverse myelitis • Hematology

Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage

disorders, or other causes ... • Secondary Causes ... deficiencies - PNH ... Differential #Diagnosis #hematology ... #rheumatology #

Recurrent / Breakthrough DVT During Anticoagulation

Subtherapeutic Anticoagulation
Hypercoagulable State
- Antithrombin deficiency
- Hypercoagulability ot

APLS - MPN/PNH ... Structural - Pelvic masses ... anticoagulation #hematology

Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
-

Causes of Extravascular ... • PCH • PNH ... Diagnosis #Algorithm #Causes ... #Hematology

Raynaud's Phenomenon on Physical Exam

#Raynauds #Syndrome #disease #phenomenon #clinical #video #physicalexam #fingers #hands #rheumatology

disease #phenomenon #clinical ... #video #physicalexam ... fingers #hands #rheumatology

Pathology - Hepatocyte Pigments

Lipofuschin (H&E)

Alpha-I-antitrypsin globules (PAS-D)

Mallory's hyaline / Mallory Denk Bodies

Giant Mitochondria

Alpha-I-antitrypsin globules (PAS-D ... ceroid-laden macrophage (PAS-D ... Pigments #Pathology #Hepatology ... #Clinical #Microscopy

Sebaceous hyperplasia
- Yellow papule
- Donut-shape
- Central umbilication
- Telangiectasia

Usually multiple - Causes ... #Hyperplasia #Dermatology ... Diagnosis #Benign #Clinical

Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell

of Sickle Cell Crises ... Clinical Manifestations ... Diagnosis #Management #Hematology

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