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diagnosis management rheumatology dermatology lupus sle differential skinrash syndrome systemic activation alkaline alp antinxp2 antinxp2dm cerebritis cns comparison dermatomyositis druginduced
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... (SLE) Clinical ... autoantibodies that will cause ... APS), Secondary ... #rheumatology #
Eczematous Skin Rash - Differential Diagnosis Algorithm Eczematous - Pruritic/Scaly/Erythematous lesions. Usually poorly demarcated • Atopic Dermatitis
Eczematous Skin Rash ... Differential Diagnosis Algorithm ... Secondary to venous ... Differential #Diagnosis #Algorithm ... #causes
Papulosquamous Skin Rash - Differential Diagnosis Algorithm Erythrematous or violaceous papules & plaques with overlying scale •
Papulosquamous Skin Rash ... Differential Diagnosis Algorithm ... Erythrematous ... central clearing • Secondary ... #causes
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
Rash Secondary ... , but without treatment ... resembling rashes caused ... #Clinical #Photo ... #Dermatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... Positive in 60-80% of cases ... life-threatening • Treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Classified among the secondary ... nervous system (CNS ... Petechial or purpuric rash ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... Discontinuation of causal ... Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... pain • loss of secondary ... membrane into the CNS ... Waddling gait - Difficulty ... Phosphatase: • Other causes
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
other diseases • Secondary ... Hypocomplementemia • Can cause ... salivary ducts Clinical ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
subcutaneous edema Pts ... rash on the face ... auricular papules Clinical ... Muscle atrophy may cause ... positive patients Treatment
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