14 results
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Testosterone - Coumadin skin ... • Nephrotic Syndrome ... coagulation and other causes ... - COVID-19 - PNH ... pathophysiology #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... Kasabach-Merritt syndrome ... deficiencies - PNH ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Pustular Skin Lesions - Differential Diagnosis Framework

What are pustules?
• Pustules < 5-10 mm + pus
• Material
Pustular Skin Lesions ... to inflammatory skin ... SAPHO syndrome ( ... Sweet syndrome ... Differential #Diagnosis #Dermatology
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
rubbing of the skin ... Stevens-Johnson Syndrome ... syndrome, caused ... Nikolskys #Sign #TEN #Dermatology ... #PhysicalExam #
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
Diagnosis- Compatible syndrome ... , may also see skin ... Infectious: • Bacterial ... differential #diagnosis #causes ... #radiology #neurology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
) is a skin condition ... Causes: - Idiopathic ... , breast CA - Hematologic ... Acral erythema - Bacterial ... #diagnosis #dermatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... et diutinum Neurologic ... thrombosis+Pulm HTN+skin ... Amyloidosis (CVS+PNS ... Paraproteinemias #Hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... injury) • Neurologic ... Vascular Disease: Arterial ... test (this is a skin ... signs #symptoms #rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
bone, joint, and skin ... blisters containing pus ... Rule out other causes ... #Rheumatology # ... diagnosis #management #Dermatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
including retinal arterial ... cryoglobulins • Negative causes ... to medium-sized arteries ... Antiphospholipid syndrome ... #hematology