18 results
DRESS Syndrome vs SJS/TEN
DRESS
 • Latency: 2-8 weeks
 • Rash: Morbilliform
 • Mucosal involvement: 50% have
DRESS Syndrome vs ... : 2-8 weeks • Rash ... #Syndrome #SJS ... TEN #comparison #table ... #dermatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... Kasabach-Merritt syndrome ... deficiencies - PNH ... #Diagnosis #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Maculopapular rash ... reticularis Differential ... • Goodpasture syndrome ... #dermatology #rash
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... Sarcoidosis • GPA ... Antiphospholipid-antibody syndrome ... #rashes #differential
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Rash - Differential ... RA, Sjogren's, GPA ... cryoglobulins • Skin ... #Differential #
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Systemic Symptoms (DRESS ... rash in association ... Edema in 70% of cases ... Resolution > 15 days Differentials ... #Syndrome #dermatology
Pustular Skin Lesions - Differential Diagnosis Framework

What are pustules?
• Pustules < 5-10 mm + pus
• Material
- Differential ... Generalized itchy rash ... SAPHO syndrome ( ... Sweet syndrome ... #Lesions #Differential
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm

HYPOPIGMENTATION
Diffuse Congenital - Generalized hypopigmentation of
of hair, eyes, skin ... sclerosis (white "ash ... McCune Albright syndrome ... #dermatology #Differential ... Diagnosis #Algorithm #causes
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... > PR3 60% • GPA ... tract, and often causes ... mucositis - Rash ... • ANCA (Dx: GPA
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... Amyloidosis (CVS+PNS ... Paraproteinemias #Hematology ... #Monoclonal #Differential