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diagnosis differential erythematosus management sle systemic vasculitis acute aki anemia cerebritis child cns extravascular hemolysis hemolytic hyponatremia intravascular kidneyinjury limping
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
RPGN has three primary ... pathophysiologic causes ... Post-strep GN, Lupus ... differential #diagnosis #algorithm ... #rheumatology
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
Common causes of ... INTRINSINC RENAL Glomerulonephritides ... Post-infectious GN, Lupus ... NephroP #AKI #causes ... Differential #Diagnosis #nephrology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... of Systemic Lupus ... autoantibodies that will cause ... Erythematosus #SLE #CNS ... #neurology #rheumatology
Hyponatremia - Differential Diagnosis Algorithm Hypovolemic - Give volume Hypervolemic (Edematous) - Look for and treat underlying cause
treat underlying cause ... Solute Intake - Primary ... Pulmonary Diseases, CNS ... Disease, Meds ( ... #diagnosis #nephrology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
FLAGS - In all cases ... splenomegaly, abnormal neurology ... cell disease Rheumatology ... #Limping #NWB #Algorithm ... Pathway #Child #Peds
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... hemoglobinuria (PNH ... usually IgG) (e.g. lupus ... usually IgM) (e.g. primary ... differential #diagnosis #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... the context of primary ... lower extremity edema ... • May involve PNS ... Erythematosus #Diagnosis #Rheumatology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... an underlying cause ... Better call hematology ... up EPO levels Primary ... #workup #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Vaginal dryness • Primary ... Hypocomplementemia • Can cause ... acidosis • NAGMA • Glomerulonephritis ... Nephrogenic DI Hematologic ... Sjogrens #Syndrome #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
with GCA or as primary ... Rash, arthritis Primary ... , pauci-immune glomerulonephritis ... tract, and often causes ... Differential #Diagnosis #Rheumatology
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