17 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
: INR/PT, aPTT(liver ... changes), high MCV ... anemia (vegan, ... not required in all ... #Workup #hematology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
diagnosis and treatment ... and hematologic ... If other causes ... algorithm #diagnosis #management ... #hepatology #gastroenterology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic anemia ... deficiency • Liver ... deficiencies - PNH ... • HCV, HBV Not ... Differential #Diagnosis #hematology
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Diagnosis and Management ... Essentially treat the pts ... anti-Hbe, HIV, HCV ... inflammation (decr ALT ... #Treatment #Hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
of HBV • HIV/HCV ... infection with severe liver ... mg/dL) or acute liver ... #Indications #management ... #hepatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... - EBV - CMV ... Treatment: ... #oncology #hematology ... #diagnosis #management
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... membrane into the CNS ... • Pernicious anemia ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
DIC • Severe Liver ... + Bleeding Treatment ... Treat primary cause ... #treatment #management ... #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
with leukopenia, anemia ... thrombocytopenia • Liver ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Hepatic Encephalopathy Treatment
 • Lactulose:
    - Oral liquid, 30-45mL 2-4x/day, titrated to 2-4
Encephalopathy Treatment ... swallow) - Via enema ... For refractory cases ... Encephalopathy #Treatment ... #management #hepatology