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diagnosis differential management algorithm anemia disorders hemolysis intravascular leukemia product transfusion aplastic ascites chronic cirrhosis classification cll coagulation comparison dermatology
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. TTP/HUS indicates thrombotic
Algorithm for workup ... of thrombocytopenia ... the peripheral blood ... purpura/hemolytic ... , Hematology 2012
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... microangiopathy: Thrombotic thrombocytopenic ... hemoglobinuria (PNH ... Extravascular #Causes ... differential #diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... : Acute blood loss ... , Acute hemolysis ... Diagnosis #Algorithm #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... Diagnosis and Workup ... plateletcount), peripheral blood ... or if a primary hematologic ... #Workup #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... platelet decrease - PNH ... Schistocytes, thrombocytopenia ... Diagnosis #Algorithm #workup ... #hematology #testing
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
: - Thrombocytopenia ... DIC/TTP/HUS - Hemolytic ... deficiencies - PNH ... fever • Drug reactions ... Differential #Diagnosis #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... severe thrombocytopenia ... TRALI): Leading cause ... more likely to cause ... diagnosis #management #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... AIHA, Transfusion reactions ... Liver Disease, PNH ... - Peripheral Blood ... Differential #Diagnosis #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... evaluation or workup ... 1,500 cells/µL Workup ... allergy, drug reaction ... Differential #diagnosis #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Causes purpura & ... severe thrombocytopenia ... TRALI): Leading cause ... more likely to cause ... diagnosis #management #hematology
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