6 results
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
to Evaluate an Abnormal ... the PT or APTT ... K Antagonists, Heparin ... to identify the cause ... #diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... Fibrinogen: ↓ • PT ... significant fibrin clot ... INR < 2.3 - APTT ... treatment #management #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... PT and/or aPTT ... Jcortesizaguirr #Abnormal ... #PT #aPTT #Prolonged ... #differential #hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
PT and the aPTT ... (e.g. heparin contamination ... amyloidosis #Abnormal ... #PT #aPTT #Prolonged ... #differential #hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
platelet #thrombin #clot ... #PT #PTT #diagnosis ... #models #hematology ... pathophysiology #anticoagulation ... Rivaroxaban #Edoxaban #heparin
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... PT/NORMAL PTT: ... PT/ABNORMAL PTT ... Differential #Diagnosis #Hematology