6 results
diagnosis differential coagulation abnormal anemia aptt arterial bleeding bruising dic disseminated embolism extravascular hemolysis hemolytic hemostasis leukemia management pathophysiology pt
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... hemoglobinuria (PNH ... disease, Copper and lead ... #Causes #differential ... #diagnosis #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... unfractionated heparin ... e.g. heparin ... Disseminated intravascular ... #differential #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... Thrombocytopenia • Prolonged ... Treat primary cause ... #Disseminated #Intravascular ... treatment #management #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Hyperhomocysteinemia - Heparin-induced ... - Disseminated intravascular ... coagulation and other causes ... - COVID-19 - PNH ... pathophysiology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... -> AML: Blast crises ... count ↑ PLT • ↑ PBS ... #Leukemia #Hematology ... #Oncology #Diagnosis
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Acquired: • Heparin ... the PT remains prolonged ... , disseminated intravascular ... discern these causes ... Differential #Diagnosis #Hematology
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