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diagnosis differential arterial ascites childhood coagulation dic disseminated embolism immunization intravascular leukemia malignant management monoclonal paraproteinemias pediatrics thrombosis treatment vascular
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Thrombocytopenia • Prolonged ... protein C and S Pathophysiology ... Treat primary cause ... Coagulation #diagnosis #causes ... treatment #management #hematology
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
muscle spasms lead ... , altered LOC; septic ... CNS and hematologic ... #Immunization #peds ... #pediatrics #pathophysiology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Hyperhomocysteinemia - Heparin-induced ... coagulation and other causes ... - COVID-19 - PNH ... Venous #Arterial #pathophysiology ... #hematology #differential
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Amyloidosis (CVS+PNS ... Autoantibodies: • WAIHA • CAD ... Thrombosis in vascular beds-renal ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... -> AML: Blast crises ... count ↑ PLT • ↑ PBS ... #Leukemia #Hematology ... #Oncology #Diagnosis
Common Malignancies That Cause Ascites The most common malignancies causing ascites are ovarian cancer, pancreatic cancer, gastric
Malignancies That Cause ... Cancer - Can lead ... hypertension or hepatic ... Differential #Diagnosis #Hepatology ... #oncology
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