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diagnosis management algorithm anticoagulation antinxp2 antinxp2dm cancer coagulation dermatology dermatomyositis dic differential disseminated doac encephalopathy immune inflammatory intravascular iris leukemia
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Thrombocytopenia • Prolonged ... + Bleeding Treatment ... Treat primary cause ... #treatment #management ... #hematology
Treatment algorithm for VTE in Malignancy (A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
Treatment algorithm ... initiated after a LMWH lead-in ... low-molecular-weight heparin ... Anticoagulation #Management #Hematology ... #Oncology
Hepatic Encephalopathy Treatment • Lactulose: - Oral liquid, 30-45mL 2-4x/day, titrated to 2-4
Hepatic Encephalopathy ... Treatment • Lactulose ... swallow) - Via enema ... For refractory cases ... #management #hepatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... -> AML: Blast crises ... count ↑ PLT • ↑ PBS ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
compounds, alcohol, lead ... factor (GCSF) treatments ... marrow studies Treatment ... Syndromes #diagnosis #hematology ... #oncology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
• ART ↓ viral load ... pleural effusions, CNS ... • HBV, HCV - Hepatic ... unintentional weight loss, nausea ... and peripheral edema
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
generalized subcutaneous edema ... Pts have more ... Muscle atrophy may cause ... antibody positive had ... positive patients Treatment
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