13 results
diagnosis management differential leukemia mds myelodysplastic anemia aplastic apml bariatric bypass capillary cell chronic clarksons classification cll complications differentiation disease
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Causes of false- ... amyloidosis Other causes ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology ... #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... only curative treatment ... Myelodysplastic #Syndrome ... #hematology #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Can Feature A Monoclonal ... Amyloidosis and monoclonal ... Amyloidosis (CVS+PNS ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... myalgias, HoTN, edema ... diagnosis #management #hematology ... #oncology
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... pain, Diffuse edema ... Monoclonal gammopathy ... risk of pulmonary edema ... #rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... formed or don’t work ... Workup: • Complete ... #diagnosis #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
microglobulin Treatment ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... Leukemia #diagnosis #workup ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Complications after Bariatric Surgery Post Bariatric Intestinal Failure: • Severe protein malnutrition after bariatric surgery • More
Manifests with edema ... Consider refeeding syndrome ... nutrients • TPN for treatment ... Gastric bypass causes ... Gastroenterology and Hepatology
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